My Bitcoin Maxi opinion, upgrade the drive so you have the full blockchain, mempool and other tools.

If you don't care about that and want the 2 drive hybrid approach then run it like it is and it will prune the chain down to 0.5 GBs. That's what I've been running as a lightning node for the last years but don't put too many eggs in one basket aka node with a shit ton of apps. It over works the machine and can lead to issues.

What I did. I have a pruned (500 GB) Start9 lightning node and another Start9 with a larger 1TB drive running the other stuff like Next Cloud, ValueWarden, NoStrudel, back up #AlbyHub etc. I need to take my own advice and upgrade my drive so I have the full blockchain but SSDs are expensive and if it aint broke dont fix it.