For me it's the mechanisms here that have cemented to a certain extent the taste makers, incentivised appealing to these accounts for visibility to a certain extent - in their replies and boosts. The recommended users, the 'trending' lists etc. Regurgitating or even just copying bitcointwitter talking points and 'memes' is somewhat (unintentionally?) rewarded.

Obviously, you can just post whatever you like and not play along, you may find your experience is more like posting into a void, or an unread (micro)blog. Someone with a niche interest might post, they may get some interaction. I don't think people are ignoring or discouraging this, but they'll probably find they're not finding a vibrant community around many/any other topics, not getting a vibrant conversation on other topics, and feel somewhat compelled to return to the safe bets of bitcoin 'memes' and slogans, being reply guys to large follower accounts.

I think an alternative trending algo which takes into account follower numbers as a percentage for likes. Eg a 50k follower account with 70 likes should'nt be 'trending', but a 400 follower account with 20 likes could be... Something like this as a factor thrown into the mix. As well as a proper forum/topic -follow clients, rather than the twitter clone clients, could help this situation. Maybe.