I finally broke down and bought a new motherboard (using #bitcoin) to try to determine if the issue is #Qubes 4.2, or the motherboard. I strongly suspect the latter.

If so, I don't know if it's a UEFI firmware issue, a defective unit or if this make and model always mucks around with hidraw devices. Frankly, at this point, I don't care. This has taken up enough of my time and I'm not going to fall for the sunk cost fallacy this time.

Maybe someday, when I have copious amounts of spare time, I'll continue trying to solve this mystery. But that ain't today!