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Fig. 1 Kinetics of M wave variations measured after the exercise.

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"The peripheral muscle fatigue is documented in ME/CFS patients. Indeed, post exercise M-wave alterations are absent in healthy subjects, for whom the amplitude of myopotentials either does not vary or even increases with the incremental pedaling force. By contrast, in a large proportion of ME/CFS patients (60 to 70%) a dynamic cycling exercise induces a reduction of muscle membrane excitability which often persists during the post-exercise recovery period"

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