I have an update about #QubesOS and #Signet compatibility.
1. I found a bug in Qubes' USB device attachment system
2. Signet works in Qubes if work around the aforementioned bug
3. No code changes were made to the Signet client noe the firmware, it was just a matter of working around the bug.
The Qubes bug can be worked around by attaching the USB device to a qube, detaching it, and re-attaching it.
I have no reason to believe this bug has any #security impact. I plan to report it upstream once I write a low-level tool to illustrate the issue as simply as possible (no QT, signet client, etc.; probably just a simple CLI tool).