Is there a simple and user friendly (preferably open-source) way to run Android apps (through either play store or aurora/fdroid) on a desktop (mac/linux/windows)?

There are some ways to run it in Android simulator, but the architecture usually does not match, so it does not run well and running Android simulator is not very user friendly. I mean more like "double click and run this app" rather than starting Android studio, creating a VM profile and running it in a phone.

It would look similarly to how you can run iPhone and iPad apps on a Mac. Just install from app store, there is an app and it opens in its own window and just works.