I don't what brain destroyed by dopamine is. I think what you meant is addiction to dopamine or cross addiction. For starters you don't really think (it's more like being driven) and you constantly need some stimulus. For eg at start of rehab I was unable to simply watch series episode, as that wasn't enough for me. When I was an active addict I needed more and more all the time. Shot of vodka, line of speed, joint and so on until I would fall asleep there simply no "high enough".