Once you can simulate your own reality, you can simulate others too. In essence, you could create your own matrix and live within it. 

It’s possible that in such a future we no longer require a physical body. If a human can be digitized (of course we won’t be human anymore), but the “essence” of this thing that was once human could remain.

Everyone always talks about how we’d explore space, how to settle worlds too distant for human travel. Perhaps we were never meant to? Perhaps instead of traveling outward, we travel inward, into our own worlds. Within these worlds we can create our own simulations and travel through them without the constraints of space and time.

The alternative would be to become a nanobot swarm that attaches itself to traveling asteroids and exist in perpetuity (perhaps powered by radiation), traveling the vast expanse of the universe. But that begs the question: why bother, when you can just create your own.