Not really; if you request kind:0 it’ll give you what the relays have.
Only caveat would be if you’re explicitly telling it to load exclusive from cache.
nostr:npub1p5ryszcvdca78jdp5ewhu67zpyfz042m7nrha6mqx7a8wakrqrkqre5ksj if you reload Flare it still shows you an old profile?