I think folks need to know that, while there is currently NO cure, there are various routes to a cure being worked on. One or all of these are promising, and even if just one works out, we could be solving this in a decade or LESS.

I am not prepared for this mentally or emotionally, but intellectually, I'm tapping my foot...

I am confident I will see the cure in my lifetime. I will witness this.

The best part? We manage the cure for CJD and the cure to more neurodegenerative diseases is sure to follow. See ya, Alzheimer's, ALS, and more.

The thing has moved from caring about why prions misfold, to simply solving this. Let's save lives. We've had 250 years to answer the misfolding question, let's move on and save lives already. (Which means pharmaceutical cures).

Let's get this shit done and have it over with in the 2030s.