It depends.

In a H2H fight, sure. But then even a lightweight trained Bjj beats a weightlifter.

A gun, kind of equalizes physical combat, and has for centuries.

A lifter can't chase after a sprinter.

Keep in mind, i'm not arguing for being weak. I have just concluded that calisthenics, short sprints and stretching, in the style of Ido Flow and a good diet of raw organs, eggs and meats are optimal for health and strength, and strain on the body.

For instance, Gym culture is mostly based around isolated muscles, which means most of the body, the parts that don't attract girls, are weak. So that's a type weakness. I would bet on a third world cement hauler vs a gym bro, any day. Both are damaging their long term survival though.