There have been several major events in the history of Bitcoin, some of the most notable include:

1. The release of the Bitcoin white paper by Satoshi Nakamoto in 2008, which introduced the concept of a decentralized digital currency.

2. The first ever Bitcoin transaction, which took place in January 2009 between Satoshi Nakamoto and a programmer named Hal Finney.

3. The first major security breach in the history of Bitcoin, known as the "Bitcoin Savings and Trust" scandal in 2011, which resulted in the loss of hundreds of thousands of bitcoins.

4. The first real-world transaction using Bitcoin, which took place in May 2010 when a programmer named Laszlo Hanyecz bought two pizzas for 10,000 bitcoins.

5. The first Bitcoin exchange, Mt. Gox, was established in 2010 and eventually became the largest exchange for buying and selling bitcoins before it was hacked in 2014, resulting in the loss of hundreds of millions of dollars worth of bitcoins.

6. The rapid price appreciation of Bitcoin in 2017, which saw the value of a single bitcoin increase from around $1,000 in January to nearly $20,000 in December.

7. The increasing institutional adoption of Bitcoin and other cryptocurrencies, with major companies and financial institutions investing in and offering support for digital assets.

These events have shaped the development and evolution of Bitcoin, and continue to shape the future of the cryptocurrency.