I have three picks for this category.
First one is obviously Khaleesi Daenerys from a naive little girl to nephew f***. One of the most hated character.
More than that, Shakespeare's Macbeth. Then there is this protagonist in the Malayalam language movie - Joji Panachel. You can draw a parallel between Macbeth and Joji. Both driven by jealousy, greed and guilt. They both have a fitting fall. If you are ok with watching a malayalam movie with subtitle, I would say, you should try it. Worth the time.
Available on PrimeVideo... https://watch.amazon.com/detail?gti=amzn1.dv.gti.1abc43fe-9a80-f520-78e5-ddf5d955977a&territory=US&ref_=share_mac_movie&r=web