Defender. It can even run in offline mode, sometimes this will help get some more virulent stuff out.

https://learn.microsoft.com/en-us/defender-endpoint/microsoft-defender-offline

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If it's really bad refresh is an option as well. It will nuke all apps while retaining user files. Proceed with caution, and have a backup 🤙

https://support.microsoft.com/en-us/windows/reset-your-pc-0ef73740-b927-549b-b7c9-e6f2b48d275e