They work man , they break the ice , they are funny even if they fail and they show the person that you have a sense of humor and they set a playful tone.
My uncle had the WORST pick up line ever it was insanely bad :
"Hey, do you have a boyfriend?"
"Um, no."
"Are you a lesbian?"
"No?!"
"Then what is your excuse for not kissing me?"
I shit you not, he pulled a woman with that line. If you can make a girl laugh it counts for a lot.