There’s something to the DNA thing, for sure.
There are also the behavioral concepts of growing up in a sick family system of addicts. It leaves such a mark at a young age that it hamstrings many from the get go.
If you have “the bad dna” you’re at a disadvantage. But you still have the possibility to succeed.
If you have that “bad dna” 🧬 plus adults caring for you who aren’t well
Mentally, and/or are living in active addiction, you’re very, very screwed from the start. It’s a lot to overcome but not everyone succumbs.