I’ve been weighing this in my mind all day, I’ve come to conclude they don’t matter, and that this is not new. Let’s consider legacy fiat money. There are rare mint runs, coins with deformations, and currency produced in specific buildings, all of which causes people who care about such things to value them beyond their defined value. A penny with 100 bucks.
In the end, if someone likes it, let them pay for it, I don’t care about their collectibles anymore than I do your Pokémon cards. No impact on fungibility. Lebron James could sign a 1$ bill but not impact the value of all 1$bills.