I think it is possible that he did kill himself, and it is also possible that the FBI can't make any cases against the pedophiles he ensnared. But he WAS an intelligence asset, and he DID have compromat on high profile people, and the FBI knows exactly who all those people are. But won't do anything about it.
So, the prison guards don't actually like prisoners. They by law have to keep someone on suicide watch in a monitored cell where they can't commit suicide. But I can totally imagine them bending the rules, giving epstein what he needed to do it, turning off the camera temporarily, and avoiding the cell so they can't be implicated, and just let him do it. Because those prison guards hate pedophiles. I don't think they realized that this was going to make it hard to track down and capture the rest of the pedo ring. So I'm not a stickler on this idea that he was murdered. I think he might have offed himself.
And as for the high profile people involved, I think they committed their videotaped acts of perversion outside of the USA, and therefore the USA has no jurisdiction. And so the FBI can't make a case against them.
But yes I think Epstein captured this compromat in order to control them. And he was probably doing it for Mossad. And so there are lots of high profile people in the US government who do not want that information out.
Anyhow, that's what I think is most likely.