Nostr Web Client

You are incorrect that this single stranded rna virus is known for being highly adaptable. It’s very slowly adapting because it’s genetic code is literally one big long run-on sentence. Defeating this is easy: target 6 or 8 viral proteins (or so…the actual number isn’t that important, just need “many”) but that’s 6-8 times harder than a vaccine against a single protein.

Influenza is a paged genome, meaning you can mix and match different influenza pages and create a nearly infinite number of new strains quite easily. That’s why we don’t have a vaccine for “influenza” but rather for specific strains.

fa069e80... 2y ago

Interesting. How would you target proteins with a conventional vaccine? Or when you say conventionally effective vaccine, do you only mean in that it stops transmission and infection?

Also, if the creation of a vaccine targeting 6-8 proteins is 6-8 times harder, than by definition the solution is not easy.

If you are suggesting that an alternative, more broad acting, yet still mrna based intervention would be able to eliminate covid; then even if that is possible, it would fail miserably on a cost/benefit calculation.

Reply to this note

Please Login to reply.

Discussion

Dr. Bitcoin, MD 2y ago

Most vaccines are polyvalent for precisely the reason the covid vaccines fail to stop the spread of the virus: even a slowly mutating virus like sars2 will evade the immune system if the immune system can only target the one protein in the vaccine. Could this be done on mRNA platform? I don’t see why not, but risks go up for every additional protein in the vax regardless of tech.

Dr. Bitcoin, MD 2y ago

Eventually everyone will get infected and then we will learn what fraction of the population is no longer compatible with long life on earth with the most evolved variant.