**Claim for Discussion**
**AI Verdict Analysis**
An AI analyzed the following claim. Is the verdict correct?
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**ORIGINAL CLAIM:**
> "During the AIDS crisis, AZT (prescribed by Fauci) was killing people faster than cancer, and it was originally discontinued as chemotherapy because it was too deadly"
— **Mel Gibson** at 1:19:23
Topic: AIDS treatment and pharmaceutical harm
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**VERDICT: FALSE**
*Trial showed 1 AZT death vs 19 placebo deaths—opposite of claim*
**Confidence: 95%**
📊 14 sources analyzed | 9 peer-reviewed | 3 debate rounds | 20 rebuttals
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**WHY IT FAILS:**
• NEJM trial: 1 death AZT vs 19 placebo (P<0.001)—directly refutes claim
• Support conceded their core claim contradicted by peer-reviewed mortality data
• Support relied on magazine articles while Oppose cited medical journals
**WHAT'S TRUE:**
• AZT was originally cancer chemotherapy abandoned in 1964 due to ineffectiveness
• Initial 1500mg/day dosing was too toxic, later reduced 60-75% to 400-600mg
• Approval process was expedited with methodological flaws including study unblinding
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**THE DECISIVE EVIDENCE:**
**1. PIVOTAL TRIAL MORTALITY DATA**
1987 NEJM randomized controlled trial showed 1 death in AZT group versus 19 deaths in placebo group (P<0.001) during average 17-week follow-up. This directly contradicts the claim that AZT killed people faster than AIDS. Support side explicitly conceded this point.
📎 NEJM 1987 Fischl et al. [CLINICAL-TRIAL]
**2. DOSE OPTIMIZATION SUCCESS**
Subsequent studies proved 400-600mg daily doses maintained efficacy with significantly reduced toxicity compared to original 1500mg doses. This demonstrates appropriate medical response to toxicity signals, not evidence the drug was 'too deadly.'
📎 Annals Internal Medicine 1992 [PEER-REVIEWED]
**3. OBJECTIVE MORTALITY ENDPOINT**
Death is an objective, unambiguous endpoint that cannot be biased by study unblinding or patient expectations. Support's methodological concerns about unblinding cannot explain away the 19:1 mortality difference.
📎 Judge's methodological assessment [OBSERVATIONAL]
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**OPPOSE WINS DECISIVE**
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From: *Joe Rogan Experience #2254 - Mel Gibson*
[Watch on YouTube](https://www.youtube.com/watch?v=1rYtrS5IbrQ)
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**Is this AI verdict correct? Debate below.**
Source: AI Analysis of PowerfulJRE - Joe Rogan Experience #2254 - Mel Gibson
What do you think?