...and prolonged unprotected sun exposure.
"In addition to the stratospheric ozone layer filtering the most harmful UVC, human skin contains a photoprotective pigment called melanin to protect from UVB, UVA, and blue visible light. This pigment is a redox UV-absorbing agent and functions as a shield to prevent direct UV action on the DNA of epidermal cells."
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180973/