New Dietary Guidelines For Americans [PDF]
https://cdn.realfood.gov/DGA.pdf
Somatic mutations impose an entropic upper bound on human lifespan
https://www.biorxiv.org/content/10.1101/2025.11.23.689982v1
> ABSTRACT
> Somatic mutations accumulate with age and can cause cell death, but their quantitative contribution to limiting human lifespan remains unclear. We developed an incremental modeling framework that progressively incorporates factors contributing to aging into a model of population survival dynamics, which we used to estimate lifespan limits if all aging hallmarks were eliminated except somatic mutations. Our analysis reveals fundamental asymmetry across organs: post-mitotic ***cells such as neurons and cardiomyocytes act as critical longevity bottlenecks, with somatic mutations reducing median lifespan from a theoretical non-aging baseline of 430 years to 169 years.*** In contrast, proliferating tissues like liver maintain functionality for thousands of years through cellular replacement, effectively neutralizing mutation-driven decline. ***Multi-organ integration predicts median lifespans of 134-170 years*** —approximately twice current human longevity. This substantial yet incomplete reduction indicates that somatic mutations significantly drive aging but cannot alone account for observed mortality, implying comparable contributions from other hallmarks.
Microsoft drops AI sales targets in half after salespeople miss their quotas
> one US Azure sales unit set quotas for salespeople to increase customer spending on a product called Foundry, which helps customers develop AI applications, by 50 percent. Less than a fifth of salespeople in that unit met their Foundry sales growth targets. In July, Microsoft lowered those targets to roughly 25 percent growth for the current fiscal year. In another US Azure unit, most salespeople failed to meet an earlier quota to double Foundry sales, and Microsoft cut their quotas to 50 percent for the current fiscal year.
When Right-Wingers Like Maria Corina Machado Win the Nobel Prize
> She’s the smiling face of Washington’s regime-change machine, the polished spokesperson for sanctions, privatization, and foreign intervention dressed up as democracy.
Linux Performance: Almost Always Add Swap Space (2023)
https://linuxblog.io/linux-performance-almost-always-add-swap-space/
This is a pretty good discussion about pros and cons of Linux swap space.
> One notable advantage is that the Linux Kernel intelligently uses swap space to optimize memory usage. It moves rarely-used memory pages into swap, freeing up more cacheable space for frequently used pages. This helps maintain a balance between performance and memory management.
> Additionally, having swap space provides a safety net. It allows administrators to react to low memory issues gradually, preventing sudden and severe performance degradation. Properly monitoring and alerting for swap usage can further enhance this safety net.
originally posted at https://stacker.news/items/839511
Transferring Baby Boomer's knowledge to younger people
Blackrock's handout on Bitcoin (PDF)
It's pretty good too.
A newly approved ‘living drug' could save more cancer patients' lives
https://www.sciencenews.org/article/newly-approved-drug-save-cancer-patient?
>Scientists now know that a variety of factors can suppress T cells’ natural tumor-fighting abilities. So our immune systems sometimes need help to quash cancer.
originally posted at https://stacker.news/items/659083
Secure Boot is completely broken on 200+ models from 5 big device makers
>“Imagine all the people in an apartment building have the same front door lock and key. If anyone loses the key, it could be a problem for the entire building. But what if things are even worse and other buildings have the same lock and the keys?”
>To this day, key players in security—among them Microsoft and the US National Security Agency—regard Secure Boot as an important, if not essential, foundation of trust in securing devices in some of the most critical environments, including in industrial control and enterprise networks.
originally posted at https://stacker.news/items/623885
Israel's ultra-Orthodox see religious study as their part in protecting state
>The ultra-Orthodox see their full-time religious study as their part in protecting the state. Many fear that greater contact with secular society through the military will distance adherents from strict observance of the faith.
>Ultra-Orthodox men attend special seminaries that focus on religious studies, with little attention on secular topics like math, English or science. Critics have said they are ill-prepared to serve in the military or enter the secular work force.
If they get drafted into the army who will be spiritually protecting Israel?
SEC caught lying
Spurious Correlations
https://www.tylervigen.com/spurious-correlations
Includes "Explanations made up by AI"
Eclipses May Generate Atmospheric Shocks
https://www.universetoday.com/14435/solar-sonic-boom-eclipses-may-generate-atmospheric-shocks/
>Eves thinks his explanation may also help to explain other phenomena during eclipses. Infrasound may be responsible for strange Foucault pendulum behaviour (the sensitive pendulums – used to demonstrate the rotation of the Earth – swing wildly during eclipses). The infrasound pulses may cause the ground to vibrate, interfering with the pendulum swing. Infrasound may also explain some bizarre animal behaviour during these events. Sub audible sound wave frequencies are known to distress or alarm birds, perhaps their strange behaviour during eclipses could be down to infrasound propagation.
As human generated data is used up, companies resort to "Synthetic data"
>“If they only train on synthetic data, they can get lost in the jungle.”
>To combat this, OpenAI and others are investigating how two different A.I. models might work together to generate synthetic data that is more useful and reliable. One system produces the data, while a second judges the information to separate the good from the bad. Researchers are divided on whether this method will work.
>A.I. executives are barreling ahead nonetheless.
>“It should be all right,” Mr. Altman said at the conference.
Exploring the Blockchain on the CLI [python]
"the Fed and its minion central banks are desperate to cut rates even in the face of inflation because the alternative is a financial collapse too big to bail out.
After all, high rates were what crashed all those banks back in March, and they never really fixed it, they just papered it over."
"Dash Jr.'s thesis seems to be that cats are the same as any other animal that Americans eat, yet many individuals witnessing the conversation are looking at their household companions in dismay. "I would never eat Mrs. Mittens," Said twitter user @babehodl69. There has been some massive backlash toward Dash Jr. as many individuals on Twitter are stuck in their logically incorrect beliefs that certain animals are beyond eating solely because they make better house animals."
"Just this week the Senate voted down a resolution that which have required a quick and full US troop drawdown from Syria, on the basis that there was never explicit Congressional authorization for the occupation in the first place."
"The governments don't want to fight inflation because that will require sacrifices. It will require admitting that we maxed the credit cards and that now we need to tighten our belts to pay them off. How many politicians in power do you know who are ready to say so openly?"
"answers common questions such as "How does the node find other peers on the network?", "How is a new block or transaction received and validated?" or "How is a transaction created and broadcasted?" along with others."
"This is primarily to ensure we can support the load for developers on GitHub and help protect the servers from being overwhelmed by anonymous requests from bots etc.'
Mail-in-a-Box helps individuals take back control of their email by defining a one-click, easy-to-deploy SMTP+everything else server: a mail server in a box
Those government databases need preventive maintenance sometimes.