when you use a statin and indirectly poison your mitochondria by decreasing the available cholesterol that is used to synthesize many of the components of your electron transport chain that generates the ATP that is necessary for energy usage in your body

statins inhibit the production of CoQ10 a crucial component of your mitochondria . it's been tried to mitigate the effects by supplementing with creatine and coq10 but unfortunately, with little success.

then when you don't produce ATP, the cycle continues with less cholesterol utilization, which drops ATP further exacerbating the stress on your system by having less cholesterol available for use which then means less ATP available.

people feel this affect with their muscle cramps went on statins because their muscles are starved of both building blocks and ATP from mitochondria poison of the statin. this is also probably the underlying mechanism for brain fog that many experience when on a statin since your brain has less ATP available.

https://pubmed.ncbi.nlm.nih.gov/31533334/

https://pmc.ncbi.nlm.nih.gov/articles/PMC12554813/?utm_source=substack&utm_medium=email