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No, mRNA vaccines do not affect your genetic structure. Here’s why:

1. mRNA Stays in the Cytoplasm – The vaccine delivers messenger RNA (mRNA) into your cells, which stays in the cytoplasm and is never integrated into your DNA, which is housed in the nucleus.

2. Temporary Effect – mRNA is naturally short-lived. After your cells use it to make the spike protein (which trains your immune system), enzymes quickly break it down and eliminate it.

3. Doesn’t Enter the Nucleus – Your DNA is inside the nucleus, and mRNA does not enter the nucleus or alter the genetic code.

4. Similar to Natural mRNA – Your body makes and destroys millions of mRNA molecules daily as part of normal cellular function. The vaccine’s mRNA works the same way.

Some confusion comes from DNA-based vaccines (like AstraZeneca or Johnson & Johnson), which use viral vectors that deliver DNA into cells. Even then, they don’t integrate into your genome—they just instruct the cell to make proteins temporarily.

The reputable scientists suggesting otherwise may be discussing hypothetical risks of DNA contamination or long-term unknowns, but there's no evidence of genome alteration in real-world data. If you want deeper technical studies on this, I can find them.

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Discussion

Lebanese Hodl 10mo ago

How long do the spike proteins live in the body when produced by the means of mRNA? What’s the advantage of getting the spike protein to be produced by the cells over protein-based vax?

curt finch 10mo ago

I'm not a microbiologist

But I'm guessing that it's cheaper, more flexible, and my more able to quickly react to new pathogens

𝙰𝚂𝙲𝙾𝚃 ↯ 9mo ago

almost half true and maybe oversimplified:

1. mRNA has a multifaceted role in the cellular environment, non-linear effects

2. mRNA vaccinations have long-lasting effects

3. RNA affects genetic material indirectly through a variety of methods

4. vaccine mRNA is more durable by design, resulting in a variety of non-linear cellular interactions

why such a statement?

curt finch 9mo ago

1. True – mRNA's role is multifaceted: it doesn't just relay genetic info but can influence translation efficiency, localization, and degradation. Cellular effects are often non-linear due to feedback and regulatory loops.

2. Partially True – The mRNA itself degrades within days, but the immune response it triggers (e.g., memory B and T cells) can be long-lasting. So the effect is long-term, not the molecule.

3. True – RNA can regulate gene expression via RNA interference, miRNAs, lncRNAs, and other pathways. These influence DNA transcription and chromatin structure indirectly.

4. Partially True – Vaccine mRNA is modified (e.g., with pseudouridine) for stability and efficient translation. This can increase interaction with ribosomes and immune sensors, potentially leading to non-linear responses, but "variety of non-linear cellular interactions" is vague and speculative without more context.