almost half true and maybe oversimplified:

1. mRNA has a multifaceted role in the cellular environment, non-linear effects

2. mRNA vaccinations have long-lasting effects

3. RNA affects genetic material indirectly through a variety of methods

4. vaccine mRNA is more durable by design, resulting in a variety of non-linear cellular interactions

why such a statement?

Reply to this note

Please Login to reply.

Discussion

1. True – mRNA's role is multifaceted: it doesn't just relay genetic info but can influence translation efficiency, localization, and degradation. Cellular effects are often non-linear due to feedback and regulatory loops.

2. Partially True – The mRNA itself degrades within days, but the immune response it triggers (e.g., memory B and T cells) can be long-lasting. So the effect is long-term, not the molecule.

3. True – RNA can regulate gene expression via RNA interference, miRNAs, lncRNAs, and other pathways. These influence DNA transcription and chromatin structure indirectly.

4. Partially True – Vaccine mRNA is modified (e.g., with pseudouridine) for stability and efficient translation. This can increase interaction with ribosomes and immune sensors, potentially leading to non-linear responses, but "variety of non-linear cellular interactions" is vague and speculative without more context.