I've got less than .2 acre. I've thought about it, but too many other projects take priority both in terms of time and space. I'd start with a small ish homebuild to collect data, then, when deciding to scale up, youll have an idea just how much capacity you'd get and how much waste you can process for a given sized system and whether your building skills and interests are up to the task.
Neither of the two best sites I found today look like the one I was looking at before, so they may have changed the layout or shadow banned it, but searches of "domestic dragon" and "dragon husbandry" have produced tons of info.