I think i have similar issue in the past. You just need to disable "people" icon in filter.nostr.wine like my settings. The spam comes from public channel first and somehow also regular notes if you enable those setting.
Discussion
Thank you as always.
I’m curious why appears in regular notes🤔
Just in amethyst and global chat... but it's gone now. Will investigate followers and follow further. But this was not spam by followers/ follows.