The more certain you are, the less you know. This isn't some throw away line. The more you foreclose the possibility of being wrong, the less likely you are to listen to arguments against your beliefs, or believe evidence that contravenes it.

I look around, and I see more and more people enslaved to a rabid certainty of what's right and what the future holds.

If you start a sentence with "nothing can convince me ..." you might well say "let me warn you, I'm a closed-minded zealot on this particular topic."