FyI you can block the latest reply spam if you are using amethyst with security filters by using the hidden words feature to block "randomuser . me" (without the space).
This is where the profile images of spam accounts are hosted and blocking this URL will block any notes that link to that host including as the profile image.
Have you tried this? Works for me.
nostr:nevent1qqs92zprn7h3txzv2de2eqmqchxqwgs5h8k60gw63x8h4z78pp4zl7qpzemhxue69uhhwmm59eek7anzd96zu6r0wd6z7q3qe26dzyg9hp5lgzf9wrpph6ux3884yxmn55pd4rxzr5exne56fsysxpqqqqqqzceer9s
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I've done that, to no avail.
🤔
Works for me, too.