There’s no way to do that. You can only mute him in your client.

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How do you mute?!! Is it a command?

I don’t know which client you’re using. On Damus, tapping the three dots on the note should bring up a menu. (Reporting the user to relays for spam is also an option, but that won’t do anything unless and until the relay operators act.)

Amathest has no mute button