The difference between many things comes down to chemistry. The answer to that particular question can be found in the upper right image.

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BAHAHAHAHA

Yes.

For the record, I was asked this once in a serious tone.

I just said no.

The concept of what one defines as a serious question appears to be changing. I think your approach is probably more rational than mine. I have found that when someone does ask something stupid, turning to look at their ear in profile and saying "blow me, I can see daylight" has negative consequences.