Depends, personally i would recommend it using both but you need to set their settings properly. In Amethyst, i can set all relays enabled for my home feed while only enable some for global feed (paid relays + filter.nostr.wine + nostr.mom + nos.lol ). nostr.mom (more strict spam filter) and nos.lol have some spam filter, lesser spam compared to another free public relay

Similar discussion:

#[3]