The Ross Ulbricht / Silk Road Case (2013 & 2020): The FBI seized 144,000 BTC directly from the Silk Road servers and Ulbricht's laptop following his arrest in a San Francisco library.
2020: The DOJ seized an additional 69,370 BTC from "Individual X," a hacker who had moved the funds from the Silk Road years earlier and agreed to forfeit them to the government.