It’s basically impossible to use it for commerce in the U.S. Not worth the effort for most businesses until we change a lot of laws and regulations.
Discussion
While the regulations indeed suck, the other countries have very similar and often worse. I think the main blocker is the mindset of the people and proliferation of very large scale solutions (like Square POSes).
The way how a lot of these communities achieved spread is by default having a solution that turns the bitcoin into fiat for the merchant. In some cases it's just a guy that in the end of the day gives you cash for the bitcoins.
This simplifies a lot of the onboarding problems. The merchant can accept bitcoin, but they get fiat and can optionally (or later) select to get bitcoin. For example in Europe Confirmo is a big provider of this solution that then all the different POSes and e-shops use. In Costa Rica, the Bitcoin Jungle team has one solution to holds the value in fiat (stablesats from Blink) and then also has a direct integration with Sinpe (like Venmo) via Bull Bitcoin.