I'm all sugar and black maple here. I think you can, it just doesn't have as much sugar in sap, you would just boil longer. I made some syrup from walnut trees for fun and it was 80 gal sap for 1 gal syrup and it was great. Sugar maple is about 45 gal sap per gallon. So big leaf maybe closer to the walnut amount. I tapped 50 walnut trees to get that because they don't give as much sap either.