Subnostr

Also there is this:

"Researchers followed 12 healthy volunteers taking part in a seven-day water-only fast. The volunteers were monitored closely on a daily basis to record changes in the levels of around 3,000 proteins in their blood before, during, and after the fast. By identifying which proteins are involved in the body's response, the researchers could then predict potential health outcomes of prolonged fasting by integrating genetic information from large-scale studies.

As expected, the researchers observed the body switching energy sources – from glucose to fat stored in the body – within the first two or three days of fasting. The volunteers lost an average of 5.7 kg of both fat mass and lean mass. After three days of eating after fasting, the weight stayed off – the loss of lean was almost completely reversed, but the fat mass stayed off. "

https://www.news-medical.net/news/20240301/Study-reveals-the-bodys-molecular-response-to-prolonged-fasting.aspx

Dissident Sound 1y ago

there could be many explanations for this strange effect and this is the type of stuff Dr. Jacob Wilson likes to study, namely the various anomalies in the body's response to both food and training ... but i'm not sure we as dilettantes should focus on odd effects like this or at least we shouldn't try to extrapolate them to general rules from a single anomaly ...

we know a body has a set point for fat mass for example - that is if you have unlimited food you will reach a certain weight and stop getting fatter.

there also appears to be a similar set point for muscle mass as well, regulated by myostatin. there was at one point an attempt to use myostatin inhibitors as super drugs for muscle building - not sure what is the status of that now.

what may have happened in this experiment is during fasting the participants dipped below their set points for both fat and muscle but were able to rebound muscle mass faster than than fat mass. if that is the explanation then there was nothing about this unique to fasting itself.

BUT it could also be some unique effect of fasting. it could be that fasting primes the body for muscle building later when protein is reintroduced into diet. i don't know.

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