We seem to need NO in small amounts but too much seems to age the body. Acts like a free radical in excess.

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It really shouldn't be surprising, it's got an excess electron, and if I am guessing correctly, it nitrates things making them acidic, similar to CO2 and acidity.

It’s definitely a free radical and is subject to antioxidant regulation but most people are low in NO more generally.

Disease is often a matter of something, even small amounts, in the wrong place for too long. I appreciate the benefits of cordyceps to police outliers.

It also helps with insulin toxicity(diabetes) and a bunch of other things. It seems promising at first glance and with the backdrop of Chinese medicine.

I think what's missing from the conversation is sun exposure. Ancestrally, we got sufficient NO from sun. Like with vitamin D, we adapted to get NO dietarily as a survival mechanism.

Just get sun exposure.