Nick Jikomes: "What is leptin? […]
Dr. Jack Kruse: "Leptin is the master hormone of the human body. […] It replaced in evolutionary history probably what melatonin used to do for us. Leptin controls your fat mass, it controls your thermodynamics, it controls appetite. Here's the big one: it controls fecundity and fertility. When you now know that 50% of people below the age of 35 are infertile, now you're beginning to understand why that's the case.
"Leptin absorbs 220nm light. That's light that is not in the sun. But leptin is in your sub-Q fat. Most people probably know that UV light doesn't penetrate really past the deepest layer of your epidermis. So then you got to ask the question, 'Well, where the hell is that light come from?' I think Nick and I have already answered that question for you definitively (it turns out when our TCA cycle is active it makes 200 to 400 nm light). If you want to learn about that, you read Roeland van Wijk's book, Light Sculpting Life, you'll learn everything you need to learn about biophotons that you didn't learn in biochemistry. And then you need to read Fritz Popp's work and put it together.
"Basically, what leptin does, it works specifically with the third semiconductor, which is melanin. And melanin comes from α-MSH, which is cleaved from POMC. POMC is the single most important gene to the mammalian tree. The mammalian tree is 200 million years old. We really got to be specialists with melanin after the KT event. Why? I believe that's when neuropsin, the UV-A detector that's present on your cornea and on your skin (which is important for Nick's story) is the link that links back to the absorption spectrum of mTOR. […] The absorption spectrum of mTOR is actually in the UV range. Anybody who's got an mTOR problem, anybody wants to live longer, you need to be in the sun longer. […] There's been six meta-analysis shown that in mammals, specifically us, that longevity is a function of how much sun we get. […] Remember what the dermatologist told you: stay out of the sun. I'm telling you: go in the sun.
[…]
"The story of Becker that I laid out in this podcast, I never want you to forget. No matter what disease you have, you can regenerate and fix it if you understand the thermodynamic givens that Nick and I talked about. […] Fully understanding the Great Oxygenation Event is so germane to you understanding the leptin-milanocortin pathway, because what is that semiconductor design around? Normoxia and the TCA cycle. […]
"Do I believe fundamentally, based on the absorption and emission spectra of all the chemicals that I've pulled out of the biochemical book, that the more time you spend in the sun, the longer you live? The answer is yes.
"What else did I learn from Doug Wallace's work on haplotypes and mitochondrial biology? I learned the older we get, the less UV light we can put in our system. We can't bury that light at the electronic state of the cell. […] That means we need more light. […]
"When a baby's born, it's 80% water. Me, as an old man now, I'm about 55% water. What did I tell you is the story of retaining that 30 million volt charge on the inner mitochondrial membrane? If you ain't got the water, then you're electrocuting yourself from inside out.
"Isn't that married to the story I told you? Because your psoriasis skin are about as old as Uncle Jack. What did I tell you to do? Deuterium-depleted water and more sun. The story that I told you is the same as the story that I'm trying to tell you about the leptin-melanocortin pathway. […]
"It's very simple. Make like the Sphinx every morning and eat like a great white shark. If you do that, you are fulfilling all in nature's wishes for you being a TCA animal that's normoxic."
Dr. Jack Kruse with Nick Jikomes @ 01:47:06–01:50:03, 53:13–53:20 & 01:51:32–01:54:37 (posted 2025-04-09) https://youtu.be/67sLlXeMg2I&t=6426