Information is related to meaning. The mind takes in and stores information, and discerns or assigns its meaning. Thus, without a subject, there is no meaning, and probably no information in any real way.
Bonaventure said that things exist in three places: in the physical world, in the mind of man, and in the mind of God. This would suggest that things do exist "out there," independent of human minds to perceive them, but that they are also given being in some way when they are grasped by the human mind. And of course, all of this depends on God as the self-existent ground of being.
God exists, and He is the Subject in which all things exist. Things exist, but they are not subjects, and so nothing else exists in them. Human beings are both things that exist and subjects in which other things can exist.
If we take God as primary, and man as secondary, then perhaps digital system are tertiary; things can exist within a computer, but the only meaningful way in which digital things exist is insofar as they exist in human minds. Does this make the digital world a sort of sub-creation?