I use Start9 for my Bitcoin needs and Umbrel for my other home server needs including the Nostr relay. I have them running on separate always on machines, though. I accidentally gained a collection of mini PCs because I like experimenting with stuff 😅 I'm also running a self-compiled node to compare reliability and ease of use.
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Awesome this is what I'm doing right now too.
Glad I'm not the only one :)