nostr:npub1nkn4k86w8advjau7hmxj0j5qx2exxgufu8cqaru7khkdgreym3ks9y3chw your point is well made. Doing a quick search of the literature, it is evident that numerous studies that appear publicly look at vaccine safety/efficacy and vaccine hesitancy among persons with Multiple Sclerosis with less evidence exploring the direct link between MS and vaccines.
Furthermore, from the quick search using Google Scholar from 2020-present, one review, Principi and Esposito (2020) state “some vaccines may induce an autoimmune neurological disease, no definitive demonstration of a potential role of vaccines in causing autoimmune neurological syndromes is presently available.” Additionally, Stefanou et al. (2023) systematic review and meta-analysis on COVID-19 vaccines and patients with MS, shows “no risk of relapse or serious adverse events” among the data analyzed in the study.
To your point about the need for cohort studies over time and the gap in the literature, Sefanou et al’s study does not focus on previous vaccination and onset of MS overtime. Rather Stefanou et al, makes the conclusion, “these safety data provide compelling pro-vaccination arguments for MS patients.”
The underlying thesis to Stefanou et al, possibly comes from a germ theory premise. Instead of asking could there be a way to prevent risk of the infectious disease by strengthening the terrain, a persons condition, before advising a vaccine?
This type of thinking is not weighted enough in medical and public health science. Also, this might be why the true causes of many disease are not identified in the scientific literature lending to an endless hamster wheel of ongoing research calling for more study. When we could be advancing the science more from a root cause perspective.
Note: These thoughts come from a preliminary search. Maybe there is more robust data out there on these topics?
Principi and Esposito (2020)
https://doi.org/10.3389/fpubh.2020.00361
Stefanou et al. (2023)
https://doi.org/10.1177/13524585221150881