Seems pretty dependent on what relays you've got configured. Although idk how nostr works well enough to determine exactly how they're so good w/ the reply
Discussion
Fairly easy to mute
Yea. Unlike the queefs coming out of my girlfriends bedroom. 
When you mute them, are you still seeing them count in the number of replies to a note? I do on Amethyst.
So I'll click on a note that says it has several replies, and then it's blank, because it's just the ReplyGuy and I have it muted, but it can still annoy me, and waste a little bit of time in my life...😡