He's saying it would be more burdensome to run a Monero node vs a Bitcoin node all things equal. Which is true.
But currently it's not difficult. The hypothetical he is putting forward sounds like a good problem to have (mass opting out) but likely will not ever happen.
My guess is crypto (in the truest sense - not custodians, IOUs, exchanges, ETFs, etc that relinquish it's core value props) will continue growing, but always remain relatively niche since freedom, sovereignty, and privacy are also niche.