They did not exist in 2001:

Tesla

Facebook

X

iPhone

iPad

Kindle

3G/4G/5G

Android

YouTube

AWS

Apple App Store

Uber

Airbnb

Blockchain

#Bitcoin

Square

Stripe

Spotify

Ethereum

Instagram

Snapchat

WhatsApp

Pinterest

SpaceX

Messenger

Box

Lyft

Quora

Hulu

Nest

Reddit

Zoom

Oculus

OpenAI

#Nostr