Not necessarily. There are certain things each app does better than the others. Also, there are all sorts of different types of content now, not all of which is supported by all clients. And nostr:npub19ma2w9dmk3kat0nt0k5dwuqzvmg3va9ezwup0zkakhpwv0vcwvcsg8axkl's point is a good one about using Nostr on different devices, too.

Example: If I am on my PC, I will probably use a web client, and lately I have really been liking Jumble.social. The only downside is, Jumble's search isn't great when searching for user profiles. For that, I generally hop over to Coracle, because it will display results based on my web-of-trust, so I don't have to worry about being duped by an impostor. Coracle is really useful for finding new profiles to follow, as well. If I want to find something very specific, though, like a note posted by a specific npub, with a key word, and within a certain date range, well then I am going to open up an advanced search on Primal for that task.

Same thing goes while on my phone. I'll probably use Amethyst for most things, but go to Coracle or Jumble for things they are better suited to do. And let's not forget that if I want to read a long-form article, I am probably going to open up Habla.news or Highlighter.com, and Fountain is now a Nostr app, too, for when I want to listen to podcasts. Or if I want to get inspiration on what to have for dinner, I will open up zap.cooking.

All of them "work," but that doesn't mean I could ever be satisfied with just using one of them.