Replying to Avatar nakad.ai🔱🦁🛡️🏯📿

Paper: Amyloidogenesis of SARS-CoV-2 Spike Protein

"It is known that S-protein affects the formation of persistent amyloid-like microclots in human blood, a potential pathological cause of long COVID-19 symptoms.

In conclusion, we herein proposed a simple molecular mechanism for how SARS-CoV-2 S-protein endoproteolyzed by NE can form amyloidogenic S-peptides, such as segment 194–203, and lead to exposure of multiple amyloidogenic segments in proteolytically nicked S-protein.

The results propose taking S-protein amyloidogenesis into account when studying COVID-19 and long COVID-19 symptoms."

and S-protein based vaccines, but they couldn't publish if they wrote that.

https://pubs.acs.org/doi/10.1021/jacs.2c03925

#covid

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Orange Crush 2y ago

With vaccines being mRNA-based and most encoding full-length Spike protein, vaccines could account for transient micro clotting after treatment, however, the mRNA and its cellular-translated vaccine Spike protein would only last in circulation on the order of hours and days, respectively.

So, you are correct that a vaccine induced event may happen, but you would need to look at acute microclot events days after vaccine dosing. I think vaccine side effects are likely being systematically minimized, but in this case the facts don’t line up well with the hypothesis. You should look at T-cell diversity depletion, where vaccines or SARS-CoV2 infection reduce the diversity of your T-cell responses leaving you more susceptible to latent endemic viruses, for example, varicella (chicken pox), HSV (herpes), and (HPV) papilloma.

The problem is it is nearly impossible to separate the two: SARS-CoV2 infection and COVID Vaccine. Nearly everyone who got vaccine has been exposed to live SARS-CoV2 at this point.

Keep questioning 🤨🫡. The truth is out there 🤙

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nakad.ai🔱🦁🛡️🏯📿 2y ago

Sadly this is not the case. They tried to make the mRNA stable but it became too stable (dual use?). There are several studies that are finding mRNA linger on in the body from weeks to months. The longest they found was 60 days in a paper in Cell.

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nakad.ai🔱🦁🛡️🏯📿 2y ago

"The observed extended presence of vaccine mRNA and spike protein in vaccinee LN GCs for up to 2 months after vaccination was in contrast to rare foci of viral spike protein in COVID-19 patient LNs. We hypothesize that the abundant spike antigen in the GCs of mRNA vaccine recipient LNs may contribute to the increased breadth of viral variant RBD binding by IgG seen after vaccination, potentially due to high antigen concentrations stimulating B cells with lower affinity for Wuhan-Hu-1 spike epitopes and better binding to variant epitopes."

https://www.cell.com/cell/fulltext/S0092-8674(22)00076-9

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Orange Crush 2y ago

Thanks for sharing this—I was not aware of this data; this is very surprising and goes against common expectations for mRNA. This could explain the long-term T-cell tuning as well if the nanoparticles are accumulating stably in the lymph nodes. Very odd. The nano particles must be stable long term in certain tissues. If only we had undergone long-term safety testing. FFS 🤦‍♂️.

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Orange Crush 2y ago

Thanks for info, 10k ⚡️ of appreciation sent your way.

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nakad.ai🔱🦁🛡️🏯📿 2y ago

Thank you, so nice of you! :)