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Mike Maher: "Are you familiar with heart coherence breathing? What are your thoughts on those sort of techniques?"

Dr. Jack Kruse: "[…] Anything that is not quantized to the environment you're in I'm going to have a problem with, but anything that is is great. When you talk about that type of breathing technique, if it gets you into an alpha rhythm or a delta rhythm, those things are going to be good. But remember when we meditate, this is what people don't really understand, you're actually switching from using the TCA cycle, which is where we make the most energy, where the F₀ head spins the most, that's 9,000 protons going through it. That's actually when you need the most oxygen.

"When you're in a relaxed state or a pre-sleep state or a meditative state your ATPase goes slower, so the breathing technique also needs to go slower. But the interesting part of that that people don't realize that's when you actually shift into a more hypoxic pathway, what we like to call aerobic glycolysis, which at least in Europe, in the United States, goes by another name that's more famous called the Warburg shift. And the Warburg shift gets a bad rep from the food gurus in the United States and the biochemists in the United States; I don't know how it is over in Europe.

"But most people don't get told that there's tissues in you that normally use a Warburg metabolism when you're alive and awake. What are those areas? the fovea of the eye, which is where central vision comes from, and also your gonads, that's in women's ovaries and in your balls. And the reason why is any place that has to make cells very very quickly tends to use a Warburg metabolism. And the reason why is glucose metabolism through a Warburg shift occurs about a 100× faster than it would if you use another pathway, and that's kind of important.

"The downside of that is it creates more reactive oxygen species which obviously isn't good. So that's why the human brain when it gets Warburg shifted, say when you're looking at a cell phone too long or you're looking at a screen too long, your brain begins to use lactate. And lactate is chosen for one reason and one reason only: because it decreases the ROS.

"When I say ROS to a guy like you that talks about breathing. you know this may blow your mind but this is the reason why many of the people who talk about breathing don't know shit about metabolism, because ROS is a function of how you breathe. So remember the more you breathe the more ROS you make, and that's a problem."

Dr. Jack Kruse with Mike Maher @ 04:15–07:00 (posted 2025-05-17) https://youtu.be/unUTOBIXvdc&t=255

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Everette Kunde 7mo ago

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