I don’t have all the data or the answers,
but I do know that,
like cigarettes, artificial dyes, vaccines, and seed oils, the digital world is not a natural one.
And as creatures of nature,
whether created by a big bang, evolution, God, or a combo of all three (depending on your religion),
it is my personal common sensical belief,
alongside lots of supporting anecdotal and experimental evidence that suggests the most optimal way for a human,
and any biological creature,
to live is one fully aligned with the environment they were designed for which is the natural world.