Yes, MLS is a key derivation system, what you encrypt is out of scope, so it works with any NIP, and even blossom blobs.
You can encrypt any event kind with it
At keast, that's what nostr:npub1ven4zk8xxw873876gx8y9g9l9fazkye9qnwnglcptgvfwxmygscqsxddfh and nostr:npub1klkk3vrzme455yh9rl2jshq7rc8dpegj3ndf82c3ks2sk40dxt7qulx3vt have been telling me.
Yes, MLS is a key derivation system, what you encrypt is out of scope, so it works with any NIP, and even blossom blobs.
Excellent!