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nobody
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At least two factors. Circulating cholesterol being one of them. Secondly, some level of inflammation that allows the cholesterol to get into the arterial wall. If you eliminate cholesterol, even in the presence of inflammation you theoretically would not develop atherosclerosis.

Replying to Avatar aidan

There is no good evidence that lowering cholesterol is an improvement to one’s health. In fact, the opposite may be true.

https://x.com/mangan150/status/1682046284071583745

The truth is that nobody really knows yet what part of the modern lifestyle causes heart attacks, but at this point there’s reasonably strong evidence that cholesterol is not a causal factor.

That is completely false. We know exactly the pathology of a heart attack. Have you ever looked at an autopsy of the coronary arteries of someone who died of a massive heart attack. The pathogenesis lies in the accumulation of cholesterol in the wall of the arteries.

Would have him check your apoB if he hasn't already.

And I'm really happy for you that you stand by your previous statements with no basis in fact or proof to back them up. I'm not going to apologize for speaking up against someone making statements that I think are quite ridiculous. If that makes me a petulant child, then so be it.

Well, you said "doctors are merely mindless agents of the insurance companies and hospital hire-ups, you are just following orders", no? So your statement is pretty broad and would include all "doctors". Therefore, I'm part of the conversation. Anyway, don't go to the fucking doctor then. I really don't give a shit.

Bro, I don't work for insurance companies or a hospital. Direct primary care. I follow my own orders.

You realize of course that doctors have absolutely nothing to do with what you are charged. You can thank your insurance company and the hospitals they collude with on that one.

Guess I'm just a dumb doctor. I have no idea what you are talking about.

That you are confused about the difference between doctors and cops, yes. That is the problem.

Yes. But I'm not sure what that has to do with doctors.